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Zoonotic Diseases - Learn About Its Causes, Transmission, Symptoms, and Prevention for UPSC!

Also Read Zoonotic Diseases - Learn About Its Causes, Transmission, Symptoms, and Prevention for UPSC! in Hindi

Humans, livestock, and the environment together play an important role in the origin and transmission of numerous Zoonotic diseases. The majority of these contagious diseases that impact humans have animal origins. A zoonotic pathogen (a microorganism that causes illness) might be a bacteria, virus, parasite, or contain a novel agent. It can cause infection through direct contact, contaminated Soil, food, water, habitat, etc. Even a healthy person can become ill through simple touch with them. In India and around the world, zoonotic illnesses are quite prevalent.

In this article, we will discuss Zoonotic Disease, its Meaning, Types, Causes, Symptoms, Transmission, Prevention & More UPSC IAS Exam. As this topic is an important part of the Science & Technology (Biology – Human Health and Disease) section of mains GS Paper 3.

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What is a Zoonotic Disease?

Zoonotic disease or zoonosis is any group of diseases or infections that can be naturally transmissible from vertebrate animals to people, including mammals, amphibians, reptiles, birds, and fishes. Also, large numbers of domestic and wild animals are sources of zoonotic disease, and there are numerous means of transmission. Currently, there are more than 200 known types of zoonoses that are responsible for zoonotic diseases.

History of Zoonotic diseases

The history of the most significant Zoonotic diseases and their outbreak is provided in brief in the following table:

Year An Overview
224 BC First outbreak of plague was reported.
541-46 CE The 1st plague pandemic outbreak was reported in Europe and Asia.
1346-1352 The 2nd plague pandemic known as the black death was reported in Europe.
1648 CE The first outbreaks of Yellow Fever disease occurred in Barbados.
1997 Avian influenza A (Bird Flu or H5N1)- 1st case of human infection was identified in Hongkong.
2019 SARS Cov-2 1st case identified in China.

Examples of zoonotic diseases

The details of the top 10 zoonotic diseases are as follows:

Top 10 Zoonotic Diseases An Overview
Yellow fever (YF)
  • An acute viral haemorrhagic disease.
  • It is transmitted by mosquitoes of the Aedes and Haemagogus species, which are arboviruses of the flavivirus genus.
Kyasanur forest disease (KFD)
  • It is a rare tick-borne endemic zoonotic disease that causes acute febrile hemorrhagic illness in humans and monkeys, especially in the southern part of India (Karnataka).
  • Caused by KFD virus (KFDV) which belongs to members of the genus Flavivirus and family Flaviviridae.
West Nile Virus(WNV)
  • It is a serious nervous system (neurological) infection.
  • It is most commonly spread to people by the bite of an infected mosquito (Culex mosquitoes are accepted as the primary global transmission vector).
Severe acute respiratory syndrome (SARS-CoV) & the Middle East respiratory syndrome coronavirus (MERS-CoV) SARS-CoV and MERS-CoV are transmitted from civet cats and dromedary camels to humans respectively.
The pandemic of Coronavirus disease (COVID-19)
  • It is a most communicable infectious disease.
  • Caused by – the SARS-CoV-2 virus and has been classified as a zoonotic disease.
  • No animal reservoir has yet been discovered, therefore this classification is still considered premature.
Nipah virus infection
  • Fruit bats, belonging to the pteropodidae family, are the natural host of Nipah virus.
  • India has witnessed four major outbreaks of the Nipah virus: 2001, 2007, 2018, and most recently in Kochi district, Kerala in 2019 respectively.
Malaria, Dengue and Chikungunya
  • All of these three diseases are mosquito-borne diseases (Which means they are transmitted through the bites of mosquitoes):
  1. Malaria –  Female mosquitoes of the genus Anopheles.
  2. Dengue – Aedes aegypti mosquitoes
  3. Chikungunya – Aedes aegypti mosquito and Aedes albopictus mosquitoes.
Plague
  • An infectious disease usually found in both animals and humans.
  • It is caused by the bacteria: Yersinia pestis (a zoonotic bacteria).
  • Spread by  the bite of an infected vector fleas.

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Monkey Pox – A Zoonotic Disease

Monkeypox is a viral zoonotic illness, which means it may transfer from animals to humans. It is caused by the monkeypox virus (MPXV), a member of the Orthopoxvirus genus in the Poxviridae family.

Monkeypox virus (MPXV) is a double-stranded DNA virus that is the etiological agent of the zoonotic disease monkeypox (MPX). It is divided into two genetic clades:

 

  • The Congo Basin (CB) clade or Central African Clade
  • The West Africa (WA) clade.

The symptoms of MPX: range from fever to respiratory distress and are identical to those of smallpox with the exception of lymphadenopathy.

Incubation period: 5 to 21 days.

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Classification Of Zoonotic Diseases

There are three major categories into which zoonotic diseases can be classified namely according to the etiological agents, according to the mode of transmission, and according to the reservoir host. These are discussed in detail below:

According to the Etiological Agents

All classes of disease agents (etiological agent or zoonoses) cause zoonotic disease, including bacteria, viruses, parasites and fungi that are as follows:

Classification Meaning Example of Disease
Bacterial Zoonoses A zoonosis caused by bacteria Leprosy, Bubonic plague, Anthrax, Lyme disease, etc.
Viral Zoonoses A zoonosis caused by the virus Avian influenza, Ebola virus disease (Ebola Hemorrhagic fever), Severe acute respiratory syndrome (SARS), Zika, Monkey-Pox, etc.
Parasitic Zoonoses A zoonosis caused by Parasite Trichinellosis, Cryptococcosis, etc.
Mycotic (fungal) Zoonoses A zoonosis caused by Fungi Histoplasmosis, and sporotrichosis.
Rickettsial Zoonoses A zoonosis caused by Rickettsia species – Gram-negative bacilli that live in eukaryotic cells as obligate intracellular parasites.

 

It is spread through the bites of infected ticks or mites, as well as through the excrement of infected lice or fleas.

Epidemic typhus, Q-Fever, Murine typhus, etc.
Chlamydial Zoonoses A zoonosis caused by Chlamydia psittaci Chlamydiosis
Protozoan Zoonoses A zoonosis caused by Protozoa Leishmaniasis
Note: A vector is an organism that transmits an infection while non-lethally feeding on the internal fluids of another host.

According to the Mode of Transmission

Zoonotic diseases are classified as follows according to the mode of transmission:

Transmission mode An overview Image
Direct zoonoses (Orthozoonoses)
  • Diseases that spread from one vertebrate to another via direct contact (with saliva, urine, blood, mucus, feces, or other body fluids of an infected animal or person) or a mechanical vector such as wind, water, soil, and so on.
  • Examples are Influenza, Plague, Rabies, etc.
Epidemiological maintenance cycle of rabies, a direct zoonosis (ortho zoonosis)

 

ortho zoonosis)

Cyclozoonosis
  • The agent requires more than one vertebrate species to complete its developmental cycle, but there is no invertebrate host.
  • Examples are human taeniasis and pentastomid infection.
Epidemiological maintenance cycle of taeniasis and cysticercosis (Taenia solium), a cyclozoonosis.

 

cyclozoonosis

Phero Zoonoses- (also called Metazoonoses)
  • Zoonoses require both vertebrates and invertebrates to complete their infectious cycle.
  • Examples are Plague, arbovirus infection, rickettsial infection, and Lyme borreliosis.
Epidemiological maintenance cycle of plague, a metazoonosis.

 

metazoonosis

Saprozoonosis
  • It has both vertebrate host and a pathogen’s growth site which can be found in environments other than those inhabited by animals, such as water, soil, plant material, etc.
  • Examples are listeriosis, and histoplasmosis.
Epidemiological maintenance cycle of Erysipelothrix infection, a saprozoonosis.

 

saprozoonosis.

Read more about Leucism

According to the reservoir host

The term “reservoir host” refers to the animal or organism where the pathogen typically resides, may develop, and perhaps multiplies. Classification of zoonotic disease as per the reservoir host is discussed in the table below:

Type of infection Reservoir Host
Anthropozoonosis Infections
  • Any infection that is transmitted from animals to humans.
  • Examples are the plague, rabies, leptospirosis, brucellosis, and arboviral infection.
Zooanthroponosis Infections
  • Infection that is transmitted from humans to lower vertebrates.
  • Examples are Staphylococci, streptococci, diphtheria, and enterobacteriaceae in cattle and parrots.
Amphixenosis Infections
  • Infections that are interchangeable and shared between humans and other vertebrates.
  • Examples are staphylococcusis and salmonellosis.

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Latest Update on Zoonotic Diseases

  • In July 2022- The World Health Organization (WHO) designated the monkeypox virus outbreak as an emergency, something that is reserved for diseases of the highest concern.
  • According to the World’s Forests 2022 report and a research paper that was published in the journal “Nature,” stated – “Climate change could result in more than 15,000 more cases of viral transmission to animals over the course of the next 50 years”.

Status of Zoonotic Diseases in India

  • In India, the top major diseases are rabies, brucellosis, toxoplasmosis, plague, cysticercosis, Nipah, echinococcosis, Japanese Encephalitis (JE), leptospirosis, Scrub typhus, trypanosomiasis, Crimean-Congo, hemorrhagic fever and Kyasanur forest disease (KFD).
  • The Central Bureau of Health Intelligence (CBHI) provisionally reported around 101,192 cases of dengue, 57813 cases of chikungunya, 14971 cases of H1N1, 4380 cases of kala-azar, 1674 cases of Japanese encephalitis, and 110 cases of rabies were reported in 2018.

 

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How are Zoonotic Diseases Transmitted?

Zoonotic pathogens can be spread to humans through any contact point with domestic, agricultural, and wild animals, etc. Some of the ways of transmission are

  • Direct contact – People may become ill through direct contact with an infected animal’s mucus, saliva, blood, urine, damaged skin, and other body fluids.
  • Indirect contact – Wild and domestic animals, such as cattle, dogs, cats, bats, pigs, raccoons, and rodents, carry the pathogen and pass them on via their urine, saliva, sweat, etc to nearby objects and surfaces and contaminate them.
  • Vector-borne – Being bitten by a tick, mosquito, or flea.
  • Waterborne – Drinking or contact with water-containing pathogens can infect both humans and animals.

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Causes of Zoonotic Disease

Zoonotic diseases are caused by:

  • Viruses,
  • Bacteria,
  • Parasites,
  • Fungi, etc.

These above microorganisms have the potential to infect humans and animals with a wide range of ailments, resulting in mild to fatal conditions.

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Symptoms of Zoonotic Disease

There are some typical signs and symptoms of zoonotic diseases which are described below:

Signs and Symptoms Illness
Gastrointestinal (GI) symptoms Pain, Diarrhea (can be severe), Abdominal cramps, Poor appetite, Vomiting, Nausea, etc.
Flu-like symptoms Fever, Headache, Fatigue, Body aches, and Swollen lymph nodes.
Skin symptoms Skin lesions, bite marks, scratches, rash, etc.
Respiratory symptoms sore throat, nasal congestion, or cough.

Prevention of Zoonotic Disease

Zoonotic diseases are common, however, we can try the following steps to prevent them:

    • Washing your hands: Wash hands immediately after contact with domestic and wild animals.
    • Non-Veg prevention: Avoid eating raw and undercooked meats.
    • Mosquito prevention: To avoid mosquito bites, use proper mosquito spray or gel, as well as pay attention to the cleanliness of the surroundings.
    • Food safety: Follow food safety measures like washing and cooking, and handling food properly.
    • Avoid infected zones: Do the necessary research before traveling and avoid traveling to areas where high zoonotic disease infections have spread.

 

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  • Prevention related to medical waste management: Medical waste should be disposed of using modern techniques,
  • Consultation: If you have been hurt by an animal (e.g. bits and scratches), consult and get treatment from your nearest primary hospital.

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Zoonotic Diseases – A Public Health Problem

Globally, there are estimated to be more than one billion cases of the disease and millions of deaths each year from zoonotic diseases alone. About 60 percent of emerging infectious diseases reported globally each year are zoonoses.

  • In India, Zoonotic diseases are a major public health problem. The plague alone has killed about 1.2 million people since 1898. Zoonotic diseases like Rabies, Chikungunya, Dengue, Malaria, etc., remain a serious health problem in the country.
  • According to a recent analysis, China and India may soon emerge as the two countries with the most potential for the spread of new zoonotic viral illnesses.
  • Zoonotic diseases pose severe risks to the security of the global health system.
  • Multisectoral and interdisciplinary collaborations are currently required to successfully mitigate and avoid the consequences of endemic and emerging zoonotic diseases of public health concern.
  • However, WHO continues to work with national governments, academia, non-governmental and philanthropic organizations, and regional and international partners to prevent and manage zoonotic threats and their public health, social and economic impacts.

Programs Run by India to Prevent Zoonotic Diseases

  • National Rabies Control Programme.
  • Programme for prevention and control of leptospirosis.
  • National One Health Programme for Prevention & Control of Zoonoses.
  • Inter-Sectoral coordination for Prevention and Control of Zoonotic Diseases

Conclusion

Zoonotic diseases have caused periodic outbreaks in humans globally. Most emerging infections in humans are zoonotic. The current COVID-19 is a perfect example of an identified emerging zoonotic disease that continues to cause a global pandemic. Anthropogenic factors such as modernization of animal husbandry and agriculture, destruction of wild animal habitats, mixing of wild and domestic animals, wildlife hunting, wildlife trade, changing food habits and urbanization can increase the emergence of zoonotic diseases in humans.

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